The idea of treating asthmatic attacks with smoke inhalation came to Britain from India in the 1800s. Indian asthmatics were pipe-smoking Angel’s Trumpets (Datura ferox) to relieve their symptoms. Word got back to the English physician, Dr Sims, who adopted the practice. When the Brit’s supply of Angel’s Trumpets was exhausted, they used Devil’s Trumpets (Datura stramonium) instead. Stramonium became the expert’s choice for treating asthma. At the time, tobacco, opium and cannabis were also gaining popularity as both therapeutic and recreational agents. Our famous Canadian physician, William Osler, extolled the benefits of medicated cigarettes in 1901.
As medical knowledge advanced and smoking fell into disfavour, stramonium and other medicated cigarettes (including menthol) were rebranded as a deterrent for smoking. For a brief time, the medical press supported medicated cigarettes to treat smoking addiction.
Further irony ensued after cigarettes were implicated in lung cancer.
Before the 1950s, no-one smoked filter-tipped cigarettes. Tobacco companies then tried to make cigarettes healthier by adding filters to block carcinogenic particles. Kent cigarettes decided asbestos would be a smart choice for a cigarette filter. Today, most laypeople will be able to tell you that asbestos causes lung cancer. Instead of making cigarettes safer, Kent was making them deadlier.
Inevitably, the downfall of medicated cigarettes was brought about by sociocultural factors, not a medical epiphany. In the late 1960s, the Canadian medical press reported that asthmatic teens were abusing their stramonium cigarettes and powders (Asthmador was a powder that was burned like incense to inhale its fumes).
Asthmatic kids were crushing, mixing and ingesting their prescribed treatment to get a hallucinogenic high. Some of them ended up in the hospital or dead. Stramonium is very similar to belladonna (deadly nightshade). Interestingly, Dr Sims, the first guy to write about smoking Datura for asthma in the medical press, apparently died of an overdose of belladonna.
Today, you can’t use your prescribed puffer to get high anymore, but inhaled treatments continue to be the cornerstone of asthma management.
Link: [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2844275/]